ChemInform Abstract: Catalytic Approach for the Formation of Optically Active Allyl α-Amino Acids by Addition of Allylic Metal Compounds to α-Imino Esters.
✍ Scribed by Xiangming Fang; Mogens Johannsen; Sulan Yao; Nicholas Gathergood; Rita G. Hazell; Karl Anker Joergensen
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 35 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Optically active a-amino acids are vital to life as building blocks of peptides, proteins, and many other natural products. Amino acids are also applied extensively as food additives, pharmaceuticals, and agrochemicals. Furthermore, amino acids are widely used in organic synthesis as targets, and as
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
The catalytic and asymmetric nitro-Mannich reaction of nitro compounds to α-imino esters catalyzed by chiral bisoxazoline-copper complexes [Eq. (1); Pg = protecting group] gave β-nitro-α-amino esters with excellent diastereo- and enantioselectivities. The reactions can be performed under ambient con