ChemInform Abstract: Bromoacetone: A New Protective Group for 1,2-Diols Cleavable with Zinc.
β Scribed by S. Chandrasekhar; Ch. Srinivas; M. Suresh Kumar; B. Muralidhar
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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A New Approach to the Protection of 1,2-Diols. -An easy access to the corresponding thionocarbonate-type derivatives, and, in sequence, to the methylene-type derivatives is presented, starting from cyclic and acyclic cis-diols by use of the thiocarbonyl compound (II), and the selective reducing age
The readily installed, fluoride labile protecting group Tsoc (-CO-O-Si(iPr) 3 ) for basic nitrogen is presented. Deprotection of Tsoc carbamates is orthogonal to the conditions used for deprotection of Boc,
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