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ChemInform Abstract: Asymmetric Synthesis of the Taxol and Taxotere C-13 Side Chains.

โœ Scribed by M. E. BUNNAGE; S. G. DAVIES; C. J. GOODWIN


Book ID
112021245
Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
26
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Practical Synthesis
โœ H.-J. HA; G.-S. PARK; Y.-G. AHN; G. S. LEE ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 31 KB ๐Ÿ‘ 2 views

Practical Synthesis of Taxol Side Chain. -A practical large-scale synthesis of the taxol side chain is achieved via the coupling of the chiral imine (V) with ketene acetal (II) followed by sequential reactions of lactamization, demethylation, methanolysis, and N-benzoylation. -(HA, H.-