ChemInform Abstract: Asymmetric Synthesis of Both Enantiomers of Two Acyclic Nucleoside Analogues Related to d4T and Acyclovir.
β Scribed by David F. Ewing; Virginie Glacon; Grahame Mackenzie; Christophe Len
- Book ID
- 101925888
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
enyloxy]prop-2-enyl}cytosine have been prepared in good yield from uridine and 5-methyluridine by periodate cleavage followed by a double Wittig reaction which introduces two vinyl groups. The thymine derivative underwent ring closure metathesis to give a novel synthesis of d4T.
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