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ChemInform Abstract: Asymmetric Electrophilic Substitutions at the α-Position of γ- and δ-Lactams.

✍ Scribed by Dieter Enders; Pascal Teschner; Gerhard Raabe; Jan Runsink


Publisher
John Wiley and Sons
Year
2010
Weight
44 KB
Volume
33
Category
Article
ISSN
0931-7597

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Copper-Catalyzed Facile Carbon-Carbon Bond Forming Reactions at the α-Position of α,α,γ-Trichlorinated γ-Lactams. -Treatment of trichlorinated lactams of type (I) with olefins in the presence of CuCl/BIPY offers a simple way to introduce alkyl groups at the α-position of lactams. Sequential reaction