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ChemInform Abstract: Aromatic P1 Replacements for the Highly Potent HIV-1 Protease Inhibitor Crixivan.

โœ Scribed by C. A. COBURN; M. B. YOUNG; R. W. HUNGATE; R. C. A. ISAACS; J. P. VACCA; J. R. HUFF


Book ID
112042017
Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
27
Category
Article
ISSN
0931-7597

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ChemInform Abstract: The Synthesis and E
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The Synthesis and Evaluation of Cyclic Ureas as HIV Protease Inhibitors: Modifications of the P1/P1' Residues. -Among various novel cyclic ureas compounds (VIII) show improved antiviral activity against HIV compared with the lead compounds DMP 323 and DMP 450. -(PATEL,