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ChemInform Abstract: Applications of the Mitsunobu Reaction in Peptide Chemistry

โœ Scribed by K. WISNIEWSKI; A. S. KOLDZIEJCZYK; B. FALKIEWICZ


Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
29
Category
Article
ISSN
0931-7597

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Alkylation of Pyrazolones via the Mitsunobu Reaction. -Mitsunobu coupling of pyrazolinone (I) or 4-acylated analogues with simple alcohols results in a preferred or exclusive O-alkylation depending on the solvent used. This mild and effective method allows the preparation of products which are not