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ChemInform Abstract: An Efficient and Versatile Method for the Preparation of α-Keto Acid Derivatives from Terminal Alkenes.

✍ Scribed by Y.-S. HON; W.-C. LIN

Book ID
112026862
Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
27
Category
Article
ISSN
0931-7597

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An efficient method for synthesis of α-k
An efficient method for synthesis of α-keto acid esters from terminal alkynes
✍ Lian-Sheng Li; Yu-Lin Wu 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 133 KB

a-Keto acid esters can be easily prepared in high yields in two steps from terminal alkynes via bromination and oxidation. This strategy provides a versatile access to the synthesis of biologically important natural products with an a-keto acid moiety.