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An efficient and versatile method for the preparation of α-keto acid derivatives from terminal alkenes

✍ Scribed by Yung-Son Hon; Wei-Chih Lin


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
231 KB
Volume
36
Category
Article
ISSN
0040-4039

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An efficient method for synthesis of α-k
✍ Lian-Sheng Li; Yu-Lin Wu 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 133 KB

a-Keto acid esters can be easily prepared in high yields in two steps from terminal alkynes via bromination and oxidation. This strategy provides a versatile access to the synthesis of biologically important natural products with an a-keto acid moiety.