A Convenient Large-Scale Synthesis of Ethyl (2-Cyanoimino-5,6dichloro-1,2,3,4-tetrahydroquinazoline-3-yl)acetate. -A practical industrial scale synthesis of the title compound (III), a key intermediate in the synthesis of the drug anagrelide, starting from glycinate (I) is accomplished.
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ChemInform Abstract: An Alternative Synthesis of Ethyl 3-(2-Chloro-4,5-difluorophenyl)-3- oxopropionate and Ethyl 3-(2,6-Dichloro-5-fluoropyridin-3-yl)-3- oxopropionate.
โ Scribed by F. J. URBAN; B. S. MOORE; P. L. SPARGO
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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