ChemInform Abstract: Synthesis of 2-(2,6-Dichloro-4-pyridyl)-3-propargyl-5-ethyl-6-methyl-4( 3H)-pyrimidinone, a Promising New Herbicide.

✍ Scribed by E. C. TAYLOR; P. ZHOU; C. M. TICE; Z. LIDERT; R. C. ROEMMELE

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 30 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199738194

✦ Synopsis

Synthesis of 2-(2,6-Dichloro-4-pyridyl)-3-propargyl-5-ethyl-6-methyl-4( 3H)-pyrimidinone, a Promising New Herbicide.

-Condensation of the Michael acceptor (I) with the amidine (II) leads to formation of the dihydropyrimidone (III) which is readily converted to the title compound (IX) by a sequence involving sigmatropic sulfoxide elimination. -(TAYLOR, E.