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ChemInform Abstract: Addition of Amino Esters to Thiiranium Ion Intermediates: A Novel Approach to the Synthesis of New Potential Aminopeptidase Inhibitors.

✍ Scribed by D. M. GILL; N. A. PEGG; C. M. RAYNER

Book ID: 112028012
Publisher: John Wiley and Sons
Year: 2010
Weight: 29 KB
Volume: 27
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199608218

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📜 SIMILAR VOLUMES

Addition of amino esters to thiiranium i

Addition of amino esters to thiiranium ion intermediates: A novel approach to the synthesis of new potential aminopeptidase inhibitors

✍ Duncan M. Gill; Neil A. Pegg; Christopher M. Rayner 📂 Article 📅 1995 🏛 Elsevier Science 🌐 French ⚖ 280 KB

ChemInform Abstract: Reaction of α-Amino

ChemInform Abstract: Reaction of α-Amino Esters and α-Amino Ester Imines with Thiiranium Ion Intermediates. Application to the Synthesis of New Potential Aminopeptidase Inhibitors and Mechanistic Implications.

✍ D. M. GILL; N. A. PEGG; C. M. RAYNER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

Reaction of α-amino esters and α-amino e

Reaction of α-amino esters and α-amino ester imines with thiiranium ion intermediates. Application to the synthesis of new potential aminopeptidase inhibitors and mechanistic implications

✍ Duncan M Gill; Neil A Pegg; Christopher M Rayner 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 829 KB

Imines derived from a-amino esters react with thiiranium ions generated in situ from 2,3-epoxy sulfides, to give an iminium ion which can be readily hydrolysed by aqueous base to liberate a secondary amine, the product of selective monoalkylation of the primary amino group. Overall yields for this p

ChemInform Abstract: Synthesis of New Po

ChemInform Abstract: Synthesis of New Potential Aminopeptidase Inhibitors by Lewis Acid Induced Rearrangement of 2,3-Epoxy Amines and Regiospecific Nucleophilic Trapping of Aziridinium Ion Intermediates with α-Amino Esters.

✍ Q. LIU; A. P. MARCHINGTON; C. M. RAYNER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB 👁 1 views

ChemInform Abstract: A New Approach to t

ChemInform Abstract: A New Approach to the Synthesis of a Key Intermediate in the Synthesis of Lincomycin.

✍ M. A. FONTES PRADO; R. J. ALVES; A. BRAGA DE OLIVEIRA; J. D. JUN. DE SOUZA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB

ChemInform Abstract: Inhibitors of Farne

ChemInform Abstract: Inhibitors of Farnesyl Transferase: A New Approach to the Development of Potential Cytostatic Drugs

✍ Martin Schlitzer 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 24 KB 👁 2 views