ChemInform Abstract: Activation of the Reverse-Cope Elimination by Allylic Oxygen Functions: Syntheses of (-)-Hygroline and (+)-Pseudohygroline.

✍ Scribed by David W. Knight; Rhys Salter

• Book ID: 101888772
• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 31 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199943210

✦ Synopsis

Activation of the Reverse-Cope Elimination by Allylic Oxygen Functions: Syntheses of (-)-Hygroline and (+)-Pseudohygroline. -The reverse-Cope cyclization of the N-(4-alkenyl)hydroxylamine (I) is remarkably accelerated by the presence of the allylic oxygen providing the precursors (II) and (III) of (-)-hygroline (VI) and (-)-pseudohygroline (VII). -(KNIGHT,