𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: A Single, Low, Oral Dose of a 5-Carbon-Linked Trioxane Dimer Orthoester Plus Mefloquine Cures Malaria-Infected Mice.

✍ Scribed by Deuk Kyu Moon; Abhai Tripathi; David Sullivan; Maxime A. Siegler; Sean Parkin; Gary H. Posner


Book ID
102071421
Publisher
John Wiley and Sons
Year
2012
Weight
16 KB
Volume
43
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Antimalarial preclinical drug developmen
✍ Deuk Kyu Moon; Vandana Singhal; Nirbhay Kumar; Theresa A. Shapiro; Gary H. Posne πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 121 KB

## Abstract Three new 5‐carbon‐linked trioxane dimer carboxylate esters have been prepared from the natural trioxane, artemisinin, in only three steps and 40–50% overall yields. Each one of these new chemical entities is at least as efficacious as the clinically used trioxane antimalarial drug arte