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ChemInform Abstract: A One-Step Protocol for the N-Chloromethylation of Heterocyclic Imides

✍ Scribed by Shu He; Hongyi Yu; Qinghong Fu; Rongze Kuang; Jeff B. Epp; William C. Groutas

Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
33
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.

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A one-pot procedure for ring enlargement
A one-pot procedure for ring enlargement of Ξ±-chloromethyl N-containing heterocycles
✍ Lianyou Zheng; Jinbao Xiang; Xu Bai πŸ“‚ Article πŸ“… 2006 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 254 KB

A simple one-pot procedure for ring enlargement of -chloromethyl N-containing heterocycles has been developed. By reaction of chloromethyl tetrahydroisoquinoline and its thieno analog with benzyl or allyl bromide under basic conditions, ring expansion and N-substitution were achieved simultaneously.