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ChemInform Abstract: A One-Pot, Three-Component Approach to Functionalized Tetrahydroisoquinolines Using Domino Heck-aza-Michael Reactions.

✍ Scribed by Daniel L. Priebbenow; Frederick M. Pfeffer; Scott G. Stewart

Publisher: John Wiley and Sons
Year: 2011
Weight: 33 KB
Volume: 42
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201128153

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A one-pot, three-component method incorporating a domino Heck-aza-Michael reaction has been developed for the rapid synthesis of functionalised tetrahydroisoquinolines. Following the in situ generation of an acrylamide, a domino process [a

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