𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: A Factor Affecting Enantioselective Reaction of a Ternary Complex of Lithium Ester Enolate with Imine.

✍ Scribed by Takeshi Kambara; Mostafa Ahmed Hussein; Hiroki Fujieda; Akira Iida; Kiyoshi Tomioka

Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
30
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.

✦ Synopsis

A Factor Affecting Enantioselective Reaction of a Ternary Complex of Lithium Ester Enolate with Imine.

-Lithiation of esters such as (I) followed by coupling of the resulting enolates with imines [cf. (II)] in the presence of chiral ether ligands is investigated systematically. Under improved reaction conditions, Ξ²-lactams (III) are obtained in up to 93% enantioselectivity.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: A Ternary Complex R
ChemInform Abstract: A Ternary Complex Reagent for an Asymmetric Reaction of Lithium Ester Enolates with Imines.
✍ H. FUJIEDA; M. KANAI; T. KAMBARA; A. IIDA; K. TOMIOKA πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 32 KB πŸ‘ 2 views

Enolates with Imines. -Based on a ternary complex reagent, which comprises three components, a chiral ether ligand, an achiral lithium amide and (I), the asymmetric addition of (I) to an imine (II) leads to the Ξ²-lactams such as (III) and (V) in high enantiomeric excess. The enantioselectivity and

ChemInform Abstract: A Ternary Complex R
ChemInform Abstract: A Ternary Complex Reagent for an Asymmetric Michael Reaction of Lithium Ester Enolates with Enoates.
✍ Yasutomo Yamamoto; Hirokazu Suzuki; Yorinobu Yasuda; Akira Iida; Kiyoshi Tomioka πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons βš– 40 KB πŸ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v