## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
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ChemInform Abstract: 4-[5-Methyl-3-phenylisoxazol-4-yl]benzenesulfonamide, Valdecoxib: A Potent and Selective Inhibitor of COX-2.
β Scribed by John J. Talley; et al. et al.
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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Diarylthiazolo(3,2b) ( 1,2,4)triazoles. -Sixteen title compounds such as (I) are prepared for evaluation of potency and selectivity against human COX-1 and COX-2 enzymes. Most of the analogues in the series are very potent against the COX-2 enzyme. All of the compounds exhibit good selectivity in