Consecutive treatment of (trifluoromethoxy)benzene with sec-butyllithium and electrophilic reagents affords previously inaccessible ortho-substituted derivatives in generally excellent yields. 2-(Trifluoromethoxy)phenyllithium acts as the key intermediate. The 3-and 4-isomers can readily be generate
ChemInform Abstract: 2-, 3-, and 4-(Trifluoromethoxy)phenyllithiums: Versatile Intermediates Offering Access to a Variety of New Organofluorine Compounds.
โ Scribed by Eva Castagnetti; Manfred Schlosser
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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