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ChemInform Abstract: (1S,2R)-((Benzyloxy)methyl)cyclopent-3-enol. A Versatile Synthon for the Preparation of 4′,1′a-Methano- and 1′,1′a-Methanocarbocyclic Nucleosides.

✍ Scribed by A. EZZITOUNI; P. RUSS; V. E. MARQUEZ


Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
28
Category
Article
ISSN
0931-7597

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A Practical Synthesis of 3-[(1R)-1-t-Butyldimethylsilyloxyethyl]-4-[(2R)-4-halo-3-oxo-2-butyl]azetidinone, a Versatile Intermediate for Carbapenem Antibiotics. -The readily available carboxylic acid (I) is converted efficiently by a three-step procedure into the title compounds such as (VI). Desily