ChemInform Abstract: Pyrimidine Thioethe
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R. A. NUGENT; ET AL. ET AL.
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Article
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2010
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John Wiley and Sons
⚖ 33 KB
👁 2 views
The effects of substituent modification on HIV-1 reverse transcriptase (RT) inhibitory activities of a series of pyrimidine derivatives, e.g. (I)-(IV), are studied. In comparison with reference compound delavirdine (DLV), compounds (Ia), (II), and (IIIa)-(IIIc) show the most potent in vitro inhibito