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Chemically induced cytogenetic damage in germinal and somatic cells of the female rabbit

✍ Scribed by R.J. DuFrain; L.G. Littlefield; J.L. Wilmer

Book ID
113249542
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
73 KB
Volume
53
Category
Article
ISSN
0165-1161

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The genotoxicity of rifampicin was tested for sister chromatic exchange in bone marrow cells and for structural chromosomal aberrations in mouse germ cells. Sister chromatid exchange frequency increased after 160, 240 and 310 mg kg-' body wt. doses but not after 80 mg kg-'. In spermatocytes, 80 mg