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Chemically bonded cyclodextrin stationary phases for liquid chromatographic separation of aromatic compounds

โœ Scribed by Kawaguchi, Yoshihiro.; Tanaka, Minoru.; Nakae, Mitsugu.; Funazo, Koichi.; Shono, Toshiyuki.


Book ID
121320700
Publisher
American Chemical Society
Year
1983
Tongue
English
Weight
803 KB
Volume
55
Category
Article
ISSN
0003-2700

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Many active drugs are racemic mixtures. Because the two enantiomers of a racemate often cause different pharmacological responses, the use of optically pure isomers is desirable and may be soon required. Cyclodextrin-bonded silica gel can be used as chiral stationary phase (CSP) in liquid chromatogr

Preparation and retention behaviour of c
โœ Minoru Tanaka; Yoshihiro Kawaguchi; Takashi Niinae; Toshiyuki Shono ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 177 KB

Both aand fl-cyclodextrin were converted into the ethylenediamine monosubstituted per-O-methyl derivatives, and the latter were coupled to succinamidopropyl silica. The resulting methylated a-cyclodextrin stationary phase improves the separation of the ortho, meta and para isomers of several disubst