## Abstract Diazepam‐^14^C and demethyldiazepam‐^14^C are synthesized from glycine‐1‐^14^C. Addition of diketene to diazepam‐^14^C leads to ketazolam‐^14^C. The reaction conditions for the formation of ketazolam from diazepam is studied using high‐pressure liquid chromatography in conjunction with
Chemical synthesis of 1-14C-octadecyldihydroxyacetone phosphate and 1-14C-octadecyldihydroxyacetone
✍ Scribed by Claude Piantadosi; Kun Chae; Khalid S. Ishaq; Fred Snyder
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 264 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0022-3549
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📜 SIMILAR VOLUMES
## Abstract Two labeled isotopomers of L‐tyrosine, L‐Tyr, have been synthesized using specific properties of the enzymes phenylanine ammonia lyase, PAL, and L‐phenylalanine hydroxylase. In an intermediate step [1‐^14^C]‐, and [2‐^14^C]‐L‐phenylalanine, L‐Phe, have been obtained from [1‐^14^C]‐, and
The title com ounds were prepared for metabolic studies, with the 14C labelen bein made a t methyl of the l-methyl-1H-tetrazol-5-ylthio ( k M d group in overall-radiochemical yglds of 26% and 22% based on barium [14C]carbonate, respectively.
## Abstract The method for the synthesis of DL‐(1‐^14^C)valine (reaction of ethyl N‐(1‐phthalimido)‐isobutyl‐1‐carbamate with K^14^CN in ethyl alcohol, followed by acidic hydrolysis of the labelled nitrile) reported by Egyed et al. (Acta Chim. Hung. 38: 123, 1963) was studied. The yield of valine c
## Abstract Reaction of adriamycinone with excess ^14^CH~3~Mgl and periodate cleavage of the resulting glycol (5) affords daunomycinone‐14‐^14^C (6). Bromination and hydrolysis of 6 gives adriamycinone‐14‐^14^C (8). Coupling of 6 and the 14‐0‐p‐anisyldiphenyl‐methyl derivative (9) with 1‐chloro‐3‐N