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Chemical mediator of insulin action stimulates lipid synthesis and down regulates the insulin receptors in primary cultures of rat hepatocytes

✍ Scribed by Jose F. Caro; Franco Folli; Frank Cecchin; Madhur K. Sinha

Book ID
115756702
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
477 KB
Volume
115
Category
Article
ISSN
0006-291X

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Extrapancreatic action of the sulphonylurea gliquidone: post-receptor effect on insulin-stimulated glycogen synthesis in rat hepatocytes in primary culture
✍ F. Rinninger; D. Kirsch; H. U. HΓ€ring; W. Kemmler πŸ“‚ Article πŸ“… 1984 πŸ› Springer 🌐 English βš– 411 KB

The effects of a sulphonylurea, gliquidone, on insulin binding and the insulin induced rate of glycogen synthesis, were studied in rat hepatocytes in primary culture. Hepatocytes were cultured for 48 h. During the second 24 h of this period, the hepatocytes were incubated with or without gliquidone