Cyclic AMP and cyclic GMP as the respective mediators of the intracycle stimulation of DNA synthesis and mitosis induced by glucagon and insulin in primary neonatal rat hepatocytes
โ Scribed by Ubaldo Armato; Paola G. Andreis; Enrica Draghi
- Book ID
- 118940569
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 392 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0024-3205
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## Abstract Purified parathyroid hormone (PTH) strongly stimulates the initiation of deoxyribonucleic acid (DNA) synthesis and thereby raises the flow of cells into mitosis in rat thymic lymphocyte populations maintained __in vitro__. These actions of PTH are potentiated by caffeine and inhibited b
Blindern, N-0316 0 t h 3 , Norway Although several lines of evidence implicate cyclic AMP in the humoral control of liver growth, its precise role is still not clear. To explore further the role of cyclic AMP in hepatocyte proliferation, we have examined the effects of glucagon and other cyclic AMP-