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Effect of down-regulation and return of insulin receptors on glycogen synthesis in cultured rat hepatocytes

✍ Scribed by Wolfgang E. Fleig; Gaby Nöther-Fleig; Sabine Steudter; Doris Enderle; Hans Ditschuneit


Book ID
119120208
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
556 KB
Volume
888
Category
Article
ISSN
0167-4889

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The effects of a sulphonylurea, gliquidone, on insulin binding and the insulin induced rate of glycogen synthesis, were studied in rat hepatocytes in primary culture. Hepatocytes were cultured for 48 h. During the second 24 h of this period, the hepatocytes were incubated with or without gliquidone