✦ LIBER ✦

Chemical Imaging of Pharmaceuticals by Time-of-flight Secondary Ion Mass Spectrometry

✍ Scribed by S. Y. Luk; N. Patel; M. C. Davies

Publisher: John Wiley and Sons
Year: 2004
Weight: 58 KB
Volume: 35
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200410300

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Imaging time-of-flight secondary ion mas

Imaging time-of-flight secondary ion mass spectrometry of solid-phase peptide syntheses

✍ Aubagnac, J.-L.; Enjalbal, C.; Drouot, C.; Combarieu, R.; Martinez, J. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 430 KB 👁 2 views

Imaging time-of-flight secondary ion mass spectrometry (TOF-SIMS) of solid-phase peptide syntheses carried out by the Merrifield and Sheppard strategies is described. Mixtures of resin beads mixed at random from batch syntheses or obtained in combinatorial chemistry by the mix and split technique, w

Characterization of adsorbed protein fil

Characterization of adsorbed protein films by time of flight secondary ion mass spectrometry

✍ Lhoest, J.-B. ;Wagner, M. S. ;Tidwell, C. D. ;Castner, David G. 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB 👁 1 views

Characterization of combinatorially desi

Characterization of combinatorially designed polyarylates by time-of-flight secondary ion mass spectrometry

✍ Anna M. Belu; Stephen Brocchini; Joachim Kohn; Buddy D. Ratner 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 114 KB 👁 2 views

A series of 16 polyarylates, with well-controlled and systematically varying chemistry, has been characterized by time-of-flight secondary ion mass spectrometry (TOF-SIMS). The polymers are structurally identical except for the incremental additions of C 2 H 4 units to the backbone and sidechain. Fr

Differentiation between protected diaste

Differentiation between protected diastereomeric trinucleotides by time-of-flight secondary ion mass spectrometry

✍ François Lafortune; Kenneth G. Standing; John B. Westmore; Masad J. Damha; Kelvi 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB

## OMS Letters Dear Sir, D if f e rent iat i on between Protect e d Dias t e reo me ric T ri nucl eo t ides by Time-of-Flight Secondary Ion Mass Spectrometry mode mass spectra (upper) and m/z 565 ions in negative mode mass spectra (lower) of ara-A%. The mechanisms depicted in the scheme may not b

Static time-of-flight secondary ion mass

Static time-of-flight secondary ion mass spectrometry imaging of freeze-fractured, frozen-hydrated biological membranes

✍ Michaeleen L. Pacholski; Donald M. Cannon Jr.; Andrew G. Ewing; Nicholas Winogra 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 704 KB

The study of cell membrane lipid and steroid composition and distribution is important for the understanding of membrane dynamics and function. Here we present efforts to chemically image phospholipid distributions on a submicron scale on freeze-fractured and frozen-hydrated liposomes and red blood

Quantitative analysis of binary adsorbed

Quantitative analysis of binary adsorbed protein films by time of flight secondary ion mass spectrometry

✍ Wagner, M. S. ;Shen, M. ;Horbett, T. A. ;Castner, David G. 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 150 KB

## Abstract Time of flight secondary ion mass spectrometry (ToF‐SIMS) is an ideal technique for the analysis of adsorbed protein films because of its surface sensitivity and chemical specificity. In this study, we examined ToF‐SIMS with the multivariate calibration method partial least squares regr