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Chemical Cleavage of Proteins at Cysteinyl-X Peptide Bonds

✍ Scribed by Bryan John Smith


Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
33
Category
Article
ISSN
0931-7597

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The chemical cleavage of amide (peptide) bonds usually requires harsh conditions. [1] As a result, side reactions and the lack of specificity of chemical amide-bond hydrolysis limits its scope in chemical biology and synthetic applications. Herein, we disclose our results on the selective cleavage o