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CHEK2, breast cancer, and the understanding of clinical utility

✍ Scribed by M Robson

Book ID
110889051
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
492 KB
Volume
78
Category
Article
ISSN
0009-9163

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## Abstract To establish the importance of __CHEK2__ mutations for familial breast cancer incidence in the German population, we have screened all 14 of the coding exons in 516 families negative for mutations in both the __BRCA1__ and __BRCA2__ genes. We found 12 distinct variants in 30 unrelated p