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303 POSTER Bilateral breast cancer — clinical features and BRCA1, BRCA2, CHEK2 mutations


Book ID
118622883
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
281 KB
Volume
3
Category
Article
ISSN
1359-6349

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We have screened index cases from 25 Russian breast/ovarian cancer families for germ-line mutations in all coding exons of the BRCA1 and BRCA2 genes, using multiplex heteroduplex analysis. In addition we tested 22 patients with breast cancer diagnosed before age 40 without family history and 6 patie