Characterization ofin vivo wear debris from ceramic?ceramic total hip arthroplasties

✍ Scribed by Lerouge, S. ;Huk, O. ;Yahia, L'H. ;Sedel, L.

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 746 KB
• Volume: 32
• Category: Article
• ISSN: 0021-9304
• DOI: 10.1002/(sici)1097-4636(199612)32:4<627::aid-jbm16>3.0.co;2-a

✦ Synopsis

In contrast to the much-studied mechanism of aseptic loosening of the metal-polyethylene joint couple, the mechanism responsible for failure of ceramic-ceramic (CC) total hip arthroplasties (THAs) has not been evaluated. The aim of this study was to conduct a systematic characterization of the in uiuo wear debris from 15 cases of CC THAs revised for aseptic loosening. Two methods were used to evaluate the wear debris; a semiquantitative histological analysis of H&Estained periprosthetic pseudomembranes; and an evaluation of isolated debris particles using SEM, energy-dispersive Xray analysis, and image analysis. The three main types of particulate debris identified were titanium alloy (TiAlV) and alumina ceramic (A1203) of prosthetic origin, and zirconium dioxide (Zr02) from the contrast agent used in the cement for prosthetic fixation. Alumina debris was present in the smallest proportion (12%) and was consistent with the low wear rate of the CC joint couple. Zirconium dioxide debris was present in the greatest proportion (76%) and was an unexpected finding. The Zr02 debris represented microstructural grains of the original ZrOz particles added as contrast agent to the cement. The presence of a histiocytic foreign body reaction to ZrO, debris on histologic sections leads us to believe that these particles play an important role in aseptic loosening of the CC THAs evaluated in this study.