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Characterization of the striatal 6-OHDA model of Parkinson's disease in wild type and α-synuclein-deleted mice

✍ Scribed by Daniel Alvarez-Fischer; Carmen Henze; Corinna Strenzke; Jan Westrich; Boris Ferger; Günter U. Höglinger; Wolfgang H. Oertel; Andreas Hartmann

Book ID
116459241
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
508 KB
Volume
210
Category
Article
ISSN
0014-4886

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## Abstract Impaired olfaction is an early symptom of Parkinson's disease. The underlying neuropathology likely includes α‐synucleinopathy in the olfactory bulb at an earlier stage (Braak's stage1) than pathology in the substantia nigra, which is not observed until stage 3. In this report, we inves