## Abstract The __in vivo__ biotransformation of dynorphin A(1–17) (Dyn A) was studied in the striatum of hemiparkinsonian rats by using microdialysis in combination with nanoflow reversed‐phase liquid chromatography/electrospray time‐of‐flight mass spectrometry. The microdialysis probes were impla
✦ LIBER ✦
Alterations in GAD67, dynorphin and enkephalin mRNA in striatal output neurons following priming in the 6-OHDA model of Parkinson's disease
✍ Scribed by A. Carta; S. Fenu; M. Morelli
- Publisher
- Springer Milan
- Year
- 2001
- Tongue
- English
- Weight
- 34 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1590-1874
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The levels of mRNAs encoding for the two isoforms of glutamate decarboxylase, GAD65 and GAD67, were measured in subpopulations of striatal neurons in adult rats depleted of dopamine as neonates with 6-OHDA and chronically injected with vehicle or with the dopamine receptor agonists apomorphine or SK