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Characterization of the human herpesvirus 8 (Kaposi’s sarcoma-associated herpesvirus) oncogene, Kaposin (ORF K12)

✍ Scribed by Sumitra Muralidhar; Gary Veytsmann; Bala Chandran; Dharam Ablashi; Jay Doniger; Leonard J Rosenthal


Book ID
117771653
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
778 KB
Volume
16
Category
Article
ISSN
1386-6532

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Nucleotide substitution at the highly po
✍ Austin L. Hughes; Mary Ann K. Hughes 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 321 KB

The K1 locus is a highly polymorphic locus in the genome of human herpesvirus 8, the causative agent of Kaposi's sarcoma. Analysis of the pattern of nucleotide substitution among alleles at this locus supported the hypothesis that natural selection has acted to enhance amino acid diversity in the tw