Lytic growth of Kaposi's sarcoma–associated herpesvirus (human herpesvirus 8) in culture
✍ Scribed by Renne, Rolf; Zhong, Weidong; Herndier, Brian; Mcgrath, Michael; Abbey, Nancy; Kedes, Dean; Ganem, Don
- Book ID
- 109927661
- Publisher
- Nature Publishing Group
- Year
- 1996
- Tongue
- English
- Weight
- 669 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1078-8956
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Recently, a novel DNA virus has been molecularly cloned from Kaposi's sarcoma (KS) tissue, a tumour common in acquired immune deficiency syndrome (AIDS). Analysis of the viral genome confirms that it is a relative of human herpesviruses and the virus has been designated HHV-8. Epidemiological eviden
We studied the seroprevalence and transmission of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8), among 215 Ugandan children, adolescents and young adults. We measured antibodies to a latent nuclear antigen (LANA) and a lytic cycle protein encoded by open reading frame (orf) 65. Infection with
## Abstract We report the molecular characterization of 38 new Kaposi's sarcoma‐associated herpesvirus (KSHV) strains from Russian patients with either classic (25 cases), epidemic/AIDS‐associated (7 cases), or posttransplant/immunosuppressed patients (6 cases), or Kaposi's sarcoma (KS). While a co