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Characterization of the adrenergic receptors regulating chloride secretion by the opercular epithelium

✍ Scribed by Susan A. May; Keith H. Baratz; Simon A. Key; Kevin J. Degnan

Publisher
Springer-Verlag
Year
1984
Tongue
English
Weight
540 KB
Volume
154
Category
Article
ISSN
0174-1578

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## Abstract The effects of ion substitutions on the Cl^βˆ’^ secretion rate and tissue conductance of isolated short‐circuited opercular epithelia from sea‐water‐adapted __Fundulus heteroclitus__ were investigated. Serosal Na^+^ substitution had the same effect on the Cl^βˆ’^ secretion rate that serosal

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The isolated, short-circuited opercular epithelium of Fundulus heteroclitus, secretes Cl- by a mechanism dependent on the presence of serosal Na+ and inhibited by bumetanide and furosemide. Under serosal Na+-free conditions the active Cl- secretion is abolished. However, subsequent elevations of int