Adrenergic regulation of chloride secretion across the opercular epithelium: The role of cyclic AMP
β Scribed by Mendelsohn, Susan A. ;Cherksey, Bruce D. ;Degnan, Kevin J.
- Publisher
- Springer-Verlag
- Year
- 1981
- Tongue
- English
- Weight
- 737 KB
- Volume
- 145
- Category
- Article
- ISSN
- 0174-1578
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The isolated, short-circuited opercular epithelium of Fundulus heteroclitus, secretes Cl- by a mechanism dependent on the presence of serosal Na+ and inhibited by bumetanide and furosemide. Under serosal Na+-free conditions the active Cl- secretion is abolished. However, subsequent elevations of int
## Abstract The effects of ion substitutions on the Cl^β^ secretion rate and tissue conductance of isolated shortβcircuited opercular epithelia from seaβwaterβadapted __Fundulus heteroclitus__ were investigated. Serosal Na^+^ substitution had the same effect on the Cl^β^ secretion rate that serosal