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Characterization of specific T helper cell activity in mice bearing alloantigenic tumors in the anterior chamber of the eye

✍ Scribed by Yasuharu Bando; Bruce R. Ksander; J. Wayne Streilein


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
1006 KB
Volume
21
Category
Article
ISSN
0014-2980

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Melanoma-specific T-cells (CTLs) are specifically cytotoxic for autologous tumor, when assayed in vitro. To examine their effectiveness in vivo, we tested the ability of these human T-cells to inhibit growth of human melanoma xenografts by using a Winn assay. Nude mice receiving specific CTLs (n = 1