Absence of an antigen-specific helper T cell required for the expression of the Tn 15 idiotype in mice treated with anti-μ antibody

Selected populations of alloreactive T c

Selected populations of alloreactive T cells contain helper T cells but lack ThId, an antigen-specific helper T cell required for dominant production of the T15 idiotype

✍ Kim Bottomly; Charles A. Janeway Jr. 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 524 KB

## Abstract Isolated, alloreactive T cell populations were primed with protein carriers __in vivo__ and tested for their ability to provide help for an anti‐phosphorylcholine (PC) antibody response and for production of the T15 idiotype. It was found that alloreactive T cell populations would suppo