Characterization of molecular and structural determinants of selective estrogen receptor downregulators
β Scribed by Meiyun Fan; Emily L. Rickert; Lei Chen; Syed A. Aftab; Kenneth P. Nephew; Ross V. Weatherman
- Publisher
- Springer US
- Year
- 2006
- Tongue
- English
- Weight
- 261 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0167-6806
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The molecular basis for recognition of peptide ligands endothelinβ1, β2 and β3 in endothelin receptors is poorly understood. Especially the origin of ligand selectivity for ET~A~ or ET~B~ is not clearly resolved. We derived sequenceβstructureβfunction relationships of peptides and recep
Uterine leiomyoma is the most frequent gynecologic neoplasm in women. By using a panel of cell lines derived from spontaneous Eker rat leiomyomas, we examined the estrogen-responsive phenotype of these tumor cells. Leiomyoma-derived ELT cell lines proliferated in response to estrogen, and estrogen-i