๐”– Bobbio Scriptorium
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Molecular aspects of phytoestrogen selective binding at estrogen receptors

โœ Scribed by Joseph V. Turner; Snezana Agatonovic-Kustrin; Beverley D. Glass

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
122 KB
Volume
96
Category
Article
ISSN
0022-3549

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The naturally occurring estrogen mimetic coumestrol has been shown to stimulate proliferation of MCF-7 mammary tumor cells and to cause uterotrophic effects in ovariectomized (OVX) rats. Attachment of a basic amine-containing sidechain to C-6 of coumestrol converts this estrogen agonist into an anta