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Characterization of Liposomes Carrying von Willebrand Factor-Binding Domain of Platelet Glycoprotein Ibα: A Potential Substitute for Platelet Transfusion

✍ Scribed by Tetsuya Kitaguchi; Mitsuru Murata; Kaori Iijima; Kaeko Kamide; Takashi Imagawa; Yasuo Ikeda

Book ID
115584190
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
224 KB
Volume
261
Category
Article
ISSN
0006-291X

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## Background and objective: Thrombus formation is initiated by adhesion of the platelet receptor, glycoprotein (gp) ib-ix-v complex, to its adhesive ligand, von willebrand factor (vwf), in the subendothelium or plasma. the vwf-binding domain of gp ib-ix-v is in the gp ibalpha subunit of the comple