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Characterization of hypervariable regions in the putative envelope protein of hepatitis C virus

✍ Scribed by Nobuyuki Kato; Yuko Ootsuyama; Showgo Ohkoshi; Takahide Nakazawa; Hitomi Sekiya; Makoto Hijikata; Kunitada Shimotohno

Book ID
115765375
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
969 KB
Volume
189
Category
Article
ISSN
0006-291X

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Genetic alterations of the putative enve
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Hypervariable region I (HVRI) of the putative second envelope glycoprotein (gp70) of hepatitis C virus (HCV) undergoes sequential alterations at intervals of several months during the chronic phase of hepatitis. To evaluate the implications of sequence variability in HVRl of HCV, we investigated the