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Using evolutionary tools to refine the new hypervariable region 3 within the envelope 2 protein of hepatitis C virus

✍ Scribed by Manuela Torres-Puente; José M. Cuevas; Nuria Jiménez-Hernández; María Alma Bracho; Inmaculada García-Robles; Borys Wrobel; Fernando Carnicer; Juan del Olmo; Enrique Ortega; Andrés Moya; Fernando González-Candelas

Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
590 KB
Volume
8
Category
Article
ISSN
1567-1348

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Hypervariable region I (HVRI) of the putative second envelope glycoprotein (gp70) of hepatitis C virus (HCV) undergoes sequential alterations at intervals of several months during the chronic phase of hepatitis. To evaluate the implications of sequence variability in HVRl of HCV, we investigated the