Characterization of a novel gene expressed exclusively in the zone of polarizing activity in the vertebrate limb
โ Scribed by Brian D. Harfe; Jason R. Rock
- Book ID
- 116975953
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 49 KB
- Volume
- 295
- Category
- Article
- ISSN
- 0012-1606
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The transplantation of small pieces of tissue from the limb buds of 9 1/2 โ 10 day hamster embryos to the wing bud of the chick results in the induction of supernumerary wing structures. The anteroposterior polarity of these induced structures is under the control of the transplanted ha
Homeobox genes play important roles in pattern formation during development. Here, we report the cloning and temporal and spatial expression patterns of a novel homeobox gene Backfoot (BFT for the human gene, and Bft for the mouse gene), whose expression reveals an early molecular distinction betwee
Pattern formation of the developing vertebrate limb is mainly controlled by the zone of polarizing activity (ZPA) and the apical ectodermal ridge (AER) which may act as sources of diffusing morphogens. These sources are tightly interconnected and maintained by positive feedback and, together with th
Over the past several decades, anatomical and electrophysiological analyses have demonstrated that the electrical activity of neurons is required for development of the precise patterns of synaptic connectivity found in the adult central nervous system. However, knowledge of the molecular cascades t