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โœฆ   LIBER   โœฆ

Electrical activity and gene expression in the development of vertebrate neural circuits

โœ Scribed by Corriveau, Roderick A.

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
146 KB
Volume
41
Category
Article
ISSN
0022-3034

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โœฆ Synopsis

Over the past several decades, anatomical and electrophysiological analyses have demonstrated that the electrical activity of neurons is required for development of the precise patterns of synaptic connectivity found in the adult central nervous system. However, knowledge of the molecular cascades that underlie activity-dependent synaptic development remains rudimentary. As a result, many fundamental issues re-main unresolved. Recent advances in differential cloning have begun to provide the tools and insight necessary to bring a molecular level of understanding to principles of activity-dependent synaptic development established via classic systems approaches.

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