## Abstract The hamster has been the accepted model of emphysema since the 1970s, demonstrating diseaseβrelated effects on respiratory skeletal muscle. However, there is scant information available about the model's ability to replicate the peripheral skeletal muscle changes seen in human disease,
Polarizing activity in the developing limb of the Syrian hamster
β Scribed by Maccabe, Jeffrey A. ;Parker, Brenda W.
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 312 KB
- Volume
- 195
- Category
- Article
- ISSN
- 0022-104X
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
The transplantation of small pieces of tissue from the limb buds of 9 1/2 β 10 day hamster embryos to the wing bud of the chick results in the induction of supernumerary wing structures. The anteroposterior polarity of these induced structures is under the control of the transplanted hamster tissue. The developing hamster limb thus has limb polarizing activity similar to that found in avian species and, as in the chick, the activity is found primarily in the posterior region of the limb bud.
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## Background: The Harderian gland (HG) is a tubulo-alveolar gland found within the ocular orbit of animals which present a nictitating membrane. The Harderian gland is regarded as an extrapineal melatonin producing organ and both, photoperiod and melatonin have been shown to exert an important ro