## Abstract A chiral stationary phase (CSP) based on (β)β(18βcrownβ6)β2,3,11,12βtetracarboxylic acid was evaluated for the direct resolution of the enantiomers of dipeptides and tripeptides. The type and concentration of the acid and the methanol content were optimized with regard to retention time
Characterization of a chiral tripeptide stationary phase for the liquid chromatographic separation of chiral dipeptides
β Scribed by Howard, William A.; Hsu, Tau Being.; Rogers, L. B.; Nelson, David A.
- Book ID
- 127215561
- Publisher
- American Chemical Society
- Year
- 1985
- Tongue
- English
- Weight
- 636 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0003-2700
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## Abstract Crown etherβbased chiral stationary phases (CSPs) have been known to be quite useful for the liquid chromatographic resolution of racemic compounds containing a primary amino group. Chiral separations on crown etherβbased CSPs are characterized by several factors. In this paper, the str
Many active drugs are racemic mixtures. Because the two enantiomers of a racemate often cause different pharmacological responses, the use of optically pure isomers is desirable and may be soon required. Cyclodextrin-bonded silica gel can be used as chiral stationary phase (CSP) in liquid chromatogr