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Characterization and Comparison of Chicken U6 Promoters for the Expression of Short Hairpin RNAs

โœ Scribed by Wise, Terry G.; Schafer, Darren J.; Lambeth, Luke S.; Tyack, Scott G.; Bruce, Matthew P.; Moore, Robert J.; Doran, Tim J.


Book ID
115315678
Publisher
Taylor and Francis Group
Year
2007
Tongue
English
Weight
410 KB
Volume
18
Category
Article
ISSN
1049-5398

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## Background The use of small interfering RNA (siRNA) molecules in animals to achieve double-stranded RNA-mediated interference (RNAi) has recently emerged as a powerful method of sequence-specific gene knockdown. As DNA-based expression of short hairpin RNA (shRNA) for RNAi may offer some advanta